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Patients have also occasionally experienced thyroid tumors

However, these modalities have demonstrated variable benefit and, due to inconsistent outcomes and tolerability constraints, have not achieved a consensus recommendation 26,32,33,34,35,36,37,38

showed that GPX3 was highly expressed in adipose tissue, and its expression was reduced in both the serum and adipose tissue of obese subjects, attributing this reduction to pro-oxidant conditions such as hypoxia and inflammation [140]

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