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doi: 10.3390/antiox12030602 69

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The tissue microarrays (TMAs) were constructed as described previously ( H -score, a combination of the proportion of positive cells and the staining intensity, was applied to assess the results of IHC

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Many preclinical studies conclusively shown that berberine plays a therapeutic role in many central nervous system disorders such as Alzheimer s disease, cerebral ischemia, depression, schizophrenia, epilepsy, and anxiety (Fan et al., 2017

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