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Stanford's classification further categorizes dissections into those involving the ascending aorta (Type A) or not (Type B) ( Oxidative stress refers to an imbalance between the production of reactive oxygen species (ROS) and endogenous antioxidant defense mechanisms

Barnish M, Sheikh M, Scholey A

This requires rigorous assessment of long-term safety, efficacy consistency in larger cohorts, optimal dosing, and compliance with regulatory standards for approval

Nucleic Acids Res 40:D720D728 McCormick M, Chen K, Ramaswamy P, Kenyon C (2011) New genes that extend Caenorhabditis elegans' lifespan in response to reproductive signals