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Wijaya, C

doi: 10.1016/j.psj.2021.101673 100

The results showed that the highest plasma concentration (Cmax) of ellagic acid reached a mean value of 33.8 12.7 ng/mL (166) at the time point of 1 h after ingestion, and the corresponding time to peak (tmax) was recorded (167)

Then, it can be verified whether it is sufficient through metabolite supplementation (rescue) under the framework of ABX + FMT, and finally test the necessity and estimate the contribution ratio through receptor/pathway blocking ( in vivo blocking), thus forming the shortest closed-loop evidence chain of key molecules-key receptors/pathways-key phenotypes