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doi: 10.1158/2159-8290.CD-19-0094 230 JanssenLMERamsayEELogsdonCDOverwijkWW

Glycocalyx degradation after cardiac arrest and resuscitation in rats induces vascular endothelial adhesion factor (VCAM-1), intercellular cell adhesion molecule-1 (ICAM-1), iNOS, and COX-2 expression, exacerbating neuronal loss, glial activation, and brain edema

These are practical considerations, not reasons to avoid the combination entirely

[DOI] [PMC free article] [PubMed] [Google Scholar] 91.Vignier N., Chatzifrangkeskou M., Rodriguez B.M., Mericskay M., Mougenot N., Wahbi K., Bonne G., Muchir A