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Description

The mechanism may involve modulation of somatostatin (GH inhibitory hormone) release from the hypothalamus, or interaction with GHRH neurons

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Delayed gastric emptying slows the entire digestive tract, reducing bowel movement frequency

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The Phase 3 TRIUMPH-4 trial pushed these numbers even higher, with the 12 mg dose achieving 28.7% mean weight loss at 68 weeks

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Scientific References Sikiric, P., et al

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