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For instance, FSP1-mediated ferroptosis can be effectively targeted for the treatment of challenging cancers, including triple-negative breast cancer (TNBC), hepatocellular carcinoma (HCC), colon cancer, acute lymphocyte leukemia and NSCLC

169 Crosstalk of NF-B signaling with Hedgehog signaling Hedgehog signaling is a highly conserved pathway with important roles in the control of cell proliferation, tissue homeostasis, tumorigenesis, and embryonic development