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Minet A, Manceau A, Valada-Mennuni A, BraultFavrou M, Churlaud C, Fort J, Nguyen TM, Spitz J, Bustamante P, LacoueLabarthe T (2020) Mercury in the tissues of five cephalopods species: first data on the nervous system

doi: 10.1016/j.mehy.2009.12.020 75 Panner SelvamMKAgarwalAHenkelRFinelliRRobertKAIovineCet al

This process is naturally inhibited by the system Xc/GSH/GPX4 regulatory pathway

In vitro studies provide further mechanistic insight, showing that lithium enhances mitochondrial function, supports oxidative balance, and prevents apoptosis through mechanisms involving cytochrome c regulation, Bcl-2 modulation, and preservation of complex I activity