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Tumor mutational burden, toxicity, and response of immune checkpoint inhibitors targeting PD(L)1, CTLA-4, and combination: a meta-regression analysis

Later, Ma et al

Settembre et al., 2012)

On the other hand, there are research results showing that, in contrast to healthy subjects, no increases in reactive nuclear factor (NF)-kB activation, interleukin-1beta (IL-1) production, antioxidant proteins (thioredoxin [TRX], Mn-SOD, heme oxygenase1 [HO-1]), or stress-protective proteins (heat shock protein-70 [HSP-70]) occurred in the quadriceps femoris muscle when COPD patients engaged in acute exercise loading [32]