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Description

Fatty acid oxidation (FAO) is used by M2 macrophages to support many tasks, such as proliferation, by supplying energy for oxidative phosphorylation and electron transfer via the TCA cycle [76]

Immunotherapy treatment Mice ( n = 60) were placed on DIO diet for 15 weeks and then were randomized to orthotopic injection with 5 10 4 metM-Wnt lung cells containing either an shRNA construct targeting GPX4 ( n = 30 mice) or a scramble shRNA construct ( n = 30 mice)