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That distinction matters, and prescribers should be clear-eyed about it

Key differences between the two enzyme families are that the -type enzymes are smaller (~35 kDa) and highly specific for reduction of oxidized Trx, whereas metazoan TrxRs are larger proteins (~55 kDa) that evolved from Gsr and are capable of reducing a broad range of substrates (Arner, 2009

Research demonstrates that it promotes synapse formation at approximately 10 million times the potency of BDNF itself, working through the hepatocyte growth factor (HGF) and c-Met receptor pathway

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