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With immunothrombosis being one of the proposed mechanisms in COVID-19 infection, we wanted to investigate this process and hypothesized that L-GSH supplementation would reduce fibrin clot formation within the PBMC cultures by reducing ROS and assisting in fibrin clearance

Peroxisomal role is also related to the function of both cellular components, namely mitochondria and ER, and therefore their dysfunction causes the production and release of H 2 O 2 in the cellular environment

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The junctional adhesion proteins (JAMs) are involved in the formation of the tight junction, and lower expression of JAM2 has been associated with CRC disease progression, metastasis and poor prognosis, indicating JAM2 as a tumour suppressor (97)