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In RA pathogenesis, activated RA fibroblast-like synoviocytes (RA-FLSs) exhibit proliferative features similar to tumor cells and subsequently cause cartilage erosion, which will eventually lead to joint destruction (1, 2)

Optimal amounts of L-glutathione are necessary for the proper function of the immune system, and to help the liver to detoxify chemicals

However, supplementation with 437.85 mg/kg glutathione significantly reduced their mRNA and protein levels

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