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For example, taking very high doses of vitamin B6 can lead to potentially irreversible nerve damage over time, while taking large amounts of niacin typically in excess of 2 grams per day can cause liver damage ( Fat-soluble vitamins Unlike water-soluble vitamins, fat-soluble vitamins do not dissolve in water and are easily stored in your bodys tissues ( There are four fat-soluble vitamins: Vitamin A Vitamin D Vitamin E Vitamin K Given that fat-soluble vitamins can accumulate in the body, these nutrients are more likely to lead to toxicity than water-soluble vitamins

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Tomin T, Bordag N, Zgner E, Al-Baghdadi A, Schinagl M, Birner-Gruenberger R, et al

It has the advantages of simple operation, low cost, repeatability and low mortality, but the disadvantage is that it is time-consuming