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Sadiq et al., 2000)

Many redox metal-containing chelates react readily with hydrogen peroxide

Alisik M, Alisik T, Nacir B, Neselioglu S, Genc-Isik I, Koyuncu P, et al

Upon exposure to oxidative or electrophilic stress, critical cysteine residues on Keap1 are modified, resulting in the stabilization and nuclear accumulation of Nrf2