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IL-23 is a cytokine involved in the inflammatory process and is considered to be associated with various chronic immune-mediated diseases

Trigonelline, a plant derived alkaloid prevents ultraviolet-B-induced oxidative DNA damage in primary human dermal fibroblasts and BALB/c mice via modulation of phosphoinositide 3-kinase-Akt-Nrf2 signalling axis

Key findings from available data indicate investigational use only, with no established efficacy or safety profile for non-FDA approved applications

Firstly, mucoglycans serve as nutrients for beneficial bacteria, enabling them to compete for mucosal colonization sites and inhibit pathogen colonization (Paone and Cani, 2020), thereby influencing mucus properties by interfering with glycosyltransferase expression, MUC2 glycosylation, and transmembrane mucin glycosylation (Schroeder, 2019