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This pathway: Promotes synaptogenesis the formation of new synaptic connections between neurons Mimics BDNF activity downstream effects on neuronal survival, plasticity, and growth Enhances hippocampal function the hippocampus is critical for memory formation and retrieval Crosses the blood-brain barrier unlike BDNF itself, Dihexa is small enough to penetrate the BBB The result is enhanced neural plasticity the brain's ability to reorganize and form new connections, which underlies learning, memory, and cognitive performance

W.JeongY.ParkS

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The evidence base is overwhelmingly preclinical, and there are no completed, published Phase 2 or 3 human efficacy trials only early-stage safety work [9]