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TFR2 was knocked down in MDA-MB-436 cells using siRNA and si-TFR2 1# was selected for further experiments, as it exhibited the highest knockdown efficiency (Fig

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British Journal of Pharmacology 153 :199-215

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doi: 10.1016/j.cell.2015.07.046 8

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This dose was slightly higher than the 1.0 mg/kg dose used in our previous studies (Degrave et al

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