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[ Links ] Porsolt RD, Anton G, Deniel M, Jalfre M (1978) Behavioral despair in rats: a new animal model sensitive to antidepressant treatments

In order to attain an 80% power at a 5% significance level in a two-sided test, each group required 40 subjects

Emerging Strategies include metabolic modulation (e.g., IGF1R inhibitors reducing glycolysis in Graves Orbitopathy fibroblasts) and selective ferroptosis induction in pathogenic cells (e.g., IKE targeting synovial fibroblasts in RA)

At times, bacterial growth was also determined by CFU at indicated time points by plating aliquots of cultures and plating appropriate dilutions on 7H11 agar plates