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Notably, moderate nutritional stress may also have positive significance for maintaining stem cell stemness

In fermented foods (such as fermented dairy products, kimchi, vinegar, and fermented dough) ( The Metabolism of Citric Acid Produces Flavor Compounds Lactic acid bacteria can produce diacetyl, acetoin, butanediol and other substances in the process of metabolizing citrate, and the secretion of related substances does not require specific transporters

Abstract Tumor microenvironment is intrinsically hypoxic with abundant hypoxia-inducible factors-1 (HIF-1), a primary regulator of the cellular response to hypoxia and various stresses imposed on the tumor cells

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