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Description

These disruptions are associated with disease subtypes, progression rates, and clinical outcomes (334, 335, 338354, 358), and studies have shown that iron chelation therapy can delay motor neuron degeneration and extend survival in ALS mouse models (352, 355, 358) ( Figure 8 )

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doi: 10.1093/brain/awy147

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[2] [3] There are two distinct phases in the pathway

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