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In vitro studies, Tan IIA (1,3 and 10 M) downregulated the expression of SR-A and upregulated the expression of ABCA1 and ABCG1 by activating the ERK/Nrf2/HO-1 signaling pathway, thereby inhibiting ox-LDL-induced cholesterol accumulation in THP-1 macrophages (Liu et al., 2014)

Plasma folate was significantly decreased in the CrO+D group, which received dietary and overload creatine, compared with the control group, the no-creatine control

Acknowledgements The authors wish to acknowledge that this manuscript is derived in part from the doctoral dissertation titled Bio-Geochemistry of ovarian cancer: Role of selenium nanoparticles in treatment and copper isotopes in detection of ovarian cancer., completed by Benoit Toubhans under the supervision of R

Protein folding involves the formation of intermediate and terminal disulfide bridges assisted by the oxidoreductase-isomerase called protein-disulfide isomerase (PDI) or its homologs ERresident protein 57 (ERP57) and ERP72 1