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However, there are IGF-I receptors on the nonparenchymal cells [89,90] and it has been reported that IGF-I stimulates both DNA synthesis [91,92] and the production of hepatocyte growth factor (HGF) in hepatic stellate cells in vitro [87]

However, depot preparations of second-generation antipsychotics (such as paliperidone and olanzapine embonate), with which such symptoms may be less common, are available