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Downregulating MYCN in IMR-5/75 decreased caspase activation for both treatments, while inducing MYCN expression in SH-SY5Y/MYCN increased caspase activation, although the differences were not statistically significant ( Figure 4D )

Changes in glucose metabolism and glycemic status with once-weekly subcutaneous semaglutide 2.4 mg among participants with prediabetes in the STEP Program