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Description

Cell 149:12691283 Lien EC, Ghisolfi L, Geck RC, Asara JM, Toker A (2017) Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT

described patients with mutations in the SLC39A8 gene, including p.Gly38Arg and compound heterozygotes p.Ile340Asn/p.Val33Met/p.Ser335Thr/p.Gly204Cys, who presented with a severe Mn deficiency 214