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Enhanced responses of Th17 cells (IL-17, IL-23) and decreased responses of Treg cells (TGF-, IL-10) and high ratios of Th17/Treg cells in SARS-CoV-2-infected patients has a strong relationship with hyperinflammation, eosinophilic responses, allergic disorders, lung damage, and COVID-19 disease pathogenesis (293)

Obesity is the major determinant of elevated C-reactive protein in subjects with the metabolic syndrome

Started with 0.1 mg subcutaneously about 45 minutes before bed

Material and methods Construction of plasmids expressing TAT-CcSOD1 fusion protein The TAT-CcSOD1 expression vectors were constructed by incorporating the coding sequences of HIV-1 TAT and CcSOD1 into the pET-24a vector