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Function of the GSTP1-G6PD-SRC complex as a metabolic signalosome Our work implies that GSTP1 plays a dominant role linking G6PD and SRC to form a signalosome that provides a basis, under metabolic stresses, for robust cancer cell proliferation upon lactic acid signaling, which could regulate many aspects of cellular metabolism

It is also involved in detoxification by binding to fat-soluble toxins, such as heavy metals, solvents, and pesticides, and transforming them into a water-soluble form that can be excreted in urine

levels of plastics and other toxins commonly found in individuals (toxins that are considered normal exposure) result in reduced levels of T3 in all tissues with the exception of the pituitary, which is resistant to the effect of toxins

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