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It is noteworthy that in another study, GA not only inhibited the activation of HSC but also suppressed the expression of proliferating cell nuclear antigen (PCNA), thereby impeding the proliferation of damaged liver cells (El-Lakkany et al., 2019)

Although human trials are still insufficient and the survival time of treated mice was not increased, researchers found both histological and functional improvement in the KD-treated ALS animal model, with higher motor neuron counts and less motor function impairment (35, 36)