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GSSG: no longer provides antioxidant protection must be recycled back into GSH to be useful again reflects how much oxidative stress the body is under High levels of oxidized glutathione signal high internal stress , not high glow

doi: 10.1007/BF00283137 27 PfeiferMASchumerMPGelberDA

Buchan SA, Seo CY, Johnson C, Alley S, Kwong JC, Nasreen S, Calzavara A, et al

4.4 Oxidative stress and mitochondrial function Oxidative stress (OS) denotes the potential harm to a cell's architecture and functionality caused by the generation and build-up of oxidizing agents, such as ROS, within and outside the cell