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However, this area is far less studied than fat metabolism

Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein

The standard dosage range of 50-150 mg daily for oral administration aligns with calculated human equivalent doses from animal research

For confirmed deficiency or pernicious anaemia, NICE Clinical Knowledge Summaries recommend hydroxocobalamin 1mg intramuscularly, with frequency determined by the underlying cause and neurological involvement