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While vitamin B12 plays a well established role in supporting metabolism and red blood cell formation, the benefits for energy and cognitive function in individuals without B12 deficiency have not been established in clinical studies

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No significant side effects were reported

In one single-center trial of 72 subjects using a controlled-adverse-environment model, the T4 eye drop did not meet its co-primary endpoints (ocular discomfort and inferior corneal staining) at the primary time point, but it did produce statistically significant improvements on several secondary endpoints, including central and superior corneal staining, with no adverse events reported