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Lancet 391 , 25472559 (2018)

This slight increase then leads to an increase in inflammatory cytokines (TNF-alpha, IL-1 beta) in macrophages[ref] Endoplasmic Reticulum (ER) stress, protein misfolding: The endoplasmic reticulum (ER) is an organelle in cells where newly synthesized proteins are folded, lipids are synthesized, and calcium is stored

The fields of earth system science, history, and planetary health continue to grapple with the causes and consequences of this Great Acceleration a proposed entry point into the Anthropocene