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Wang B, Zheng X, Liu J, et al

Clones expressing AATF or XRCC4 Dox-induced shRNAs were cloned into the Tet-pLKO-puro vector (Addgene)

Leveraging rolling circle amplification, they synthesized DNA nanoflowers with high cargo capacity and functionalized them with transferrin receptor aptamers for brain-targeted delivery