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Steven Yoelin as the Medical Director at The Skin Specialist Medical Aesthetics

The so-called GLP-1 patches contain some herbal ingredients that are claimed to have effects similar to these drugs, however, there is very limited scientific evidence to support these

Notable recent developments include the first preclinical study demonstrating NNMT inhibition improves cardiac function and reduces fibrosis in a heart failure model (Li et al., 2025), a comprehensive review of NNMT as a therapeutic target for neurodegenerative disorders (Liu et al., 2025), and emerging evidence that NNMT inhibition counteracts tubular senescence and fibrosis in chronic kidney disease

Bai B, Ma Y, Liu D, Zhang Y, Zhang W, Shi R, et al