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SGLT2 inhibitors, which confer cardiovascular benefits in T2DM patients, can also exert pro-ketogenic effects by mediating a metabolic switch from glucose to lipid utilization

forming bile salts, which play an important role in digestion

We have already seen the Cahill cycle as one example of an interorgan metabolic shuttle

(2016) reviewed the click chemistry approach to functionalize polymer NPs with sialic acid mimetics capable to express a high affinity for Siglec-3, counteracting the amyloid-beta protein deposition and plaque formation in the brain and, as a result, the Alzheimers disease progression