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) Or to state things more briefly, addition to these alkenes results in an enolate , and enolates are considerably more stable than ordinary carbanions since negative charge can be transferred to oxygen

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The downstream target gene REV-ERB of PPAR is one of the core CLOCK components [24]

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doi: 10.3390/ijms231911076 75

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In addition, APS can also downregulate the expression of NLRP3, caspase-1, and ASC in colonic tissues, thus preventing the activation of NLRP3, which in turn reduces the expression of IL-18 and IL-1 and alleviates the DSS-induced colonic inflammatory response (Tian et al., 2017)

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