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In reviews of the literature published between 1999 and 2007, Daly-Youcef [4] and Andrs E [19] concluded that orally administered vitamin B12 provided effective treatment for adult and elderly patients with deficiencies, although they highlighted that further studies were needed to determine its effectiveness in patients with severe neurological symptoms

Metabolism & aging (preclinical): NAD+-dependent sirtuin and PARP activity has been linked to DNA repair and metabolic regulation in animal models [11]

Association between abnormal maternal serum levels of vitamin B12 and preeclampsia: a systematic review and meta-analysis. Nutrition Reviews 79.5 (2021): 518-528