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While they are commonly used for weight loss, their applications can extend to other areas, such as athletic performance, mental clarity, and overall well-being

cancer treatment or remission within the past five years requires explicit clearance and ongoing supervision from the clinician managing that history

Certain antibiotics, medications used to manage diabetes, and various prescription formulations may contain alcohol-based ingredients or produce metabolites that complicate screening interpretations

Evidence also suggests that B12 deficiency can cause inflammation and damage to blood vessels, as well as oxidative stress, which combined can interrupt normal blood flow to the feet (Spence, 2016)