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Within the organ system, ROS generation can worsen to either excess or deficiency, for example, in cases of mitochondrial dysfunction or ferroptosis, which tip the balance from survival to cell death (Lewerenz et al

Buck MD, OSullivan D, Pearce EL

Contributing Centres : Unit Mixte de Gntique Constitutionnelle des Cancers Frquents, Hospices Civils de Lyon - Centre Lon Brard, Lyon, France: Nadia Boutry-Kryza, Alain Calender, Sophie Giraud, Mlanie Lone