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Boxed warnings are the most serious warnings from the Food and Drug Administration (FDA)

Appl Environ Microbiol 77(15):52575269

carinata was treated with 5 M CuSO 4 , the accumulation of His, threonine, Gln, glycine, Pro, and methionine was 140, 22, 7, 23, 6, and 13 M, respectively which could make about 67, 42, 45, 52, 60, and 33% complexation of 0.94 mol Cu under a pH of 5.8 (Irtelli et al., 2009)