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High glucose alters the DNA methylation pattern of neurodevelopment associated genes in human neural progenitor cells in vitro

Wound healing: accelerated closure in rodent excision models Collagen synthesis: type I and III collagen upregulation in fibroblast cultures Hair biology: follicle enlargement observed in organ culture models Anti-fibrotic: decorin upregulation may limit scar tissue formation Antioxidant defense: SOD and catalase gene upregulation via copper-dependent pathways Evidence Base & Study Quality A critical distinction between these two peptides is the breadth of their evidence base

Pitcher et al., Conduits mediate transport of low-molecular-weight Antigen to Lymph Node Follicles

A thorough understanding of the regulation of enzymatic and non-enzymatic crosslinks is needed to better determine how tendon mechanical properties are regulated, to guide the development of mechanically functional engineered tendon tissues, and to better characterize tendon pathogenesis