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As PEI is positively charged and DNA is negatively charged, a positive and negative zeta potential can be used to indicate whether PEI or DNA dominates at the MNP complex surface

84 MachnikM.KaiserS.KoppeS.KietzmannM.SchenkI.DueM.et al (2017)

The effects of alcoholism on brain glucose and acetate metabolism were assessed by positron emission tomography, and brain glucose metabolism was found to be reduced and acetate uptake was increased during alcoholism, suggesting that increasing acetate concentration through a KD may have therapeutic benefits for AUD (103)