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This increasing trend not only places a considerable burden on healthcare systems but also significantly affects the physical and psychological well-being of patients

Effects of acute and chronic methylphenidate administration on b-endorphin, growth hormone, prolactin and cortisol in children with attention deficit disorder and hyperactivity

Furthermore, we evaluate emerging therapeutic strategies-ranging from iron chelation and radical-trapping antioxidants to GPX4-modulating agents and advanced nanomedicine-based delivery platforms-and critically appraise the landscape of candidate biomarkers indispensable for clinical translation, encompassing circulating lipid peroxidation products, iron metabolism indices, regulatory non-coding RNAs, and advanced imaging surrogates.By integrating mechanistic insights with translational perspectives, this Review positions ferroptosis as both a fundamental driver of cardiovascular pathology and a promising frontier for the development of precision diagnostics and targeted therapies aimed at mitigating the global burden of CVD

Facilities should regularly be evaluating their training programs (scope, frequency, format, etc.) in light of available performance and quality metrics to identify opportunities for improvement