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Alternative repletion strategies have focused on oral administration of GSH precursors (e.g., cysteine and glycine supplementation 9 ), and intravenous administration of GSH, 10 which although promising, is invasive and inconvenient, and therefore unlikely to be a practical solution

It is recommended that adults over the age of 50 increase their sources of vitamin B12 through diet, fortified foods, B12 shots, or other supplements that can increase their B12 consumption. (By The National Institutes of Health) GASTROINTESTINAL ISSUES AND B12 SHOTS Persons who have gastrointestinal issues are particularly predisposed to issues with B12 deficiencies

(2015) 'Randomised, Placebo-Controlled Trial of Methyl B12 for Children with Autism', *Journal of Autism and Developmental Disorders*

Fatigue may improve with Hormone Replacement Therapy including Testosterone Replacement (TRT) and Thyroid replacement