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Intranasal Insulin Field Taking Off Insulins broad effects in the brain have lead intranasal insulin studies being attempted in a wide variety of diseases and conditions including Alzheimers, type 2 diabetes, addiction, epilepsy, depression, and to reduce anxiety and fear

Post-hoc power calculations (G*Power 3.1) using the reported effect sizes (Cohens d 0.250.40) indicate that 80% power to detect a minimal clinically important difference of 1 cm on the VAS pain scale would require 128200 completers per arm

Injections offer superior bioavailability, especially for *Vitamin B12*, which can be poorly absorbed orally in some individuals

Metabolic syndrome, which is associated with insulin resistance, has also been found at various times in both FM and ME/CFS