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The initiator of neuroexcitotoxicity and ferroptosis in ischemic stroke: glutamate accumulation

It also plays a crucial role in detoxification, helping to eliminate harmful toxins and free radicals from the body

As an important regulator of Wnt transduction in the canonical signaling pathway in tumours, Dickkopf-related protein 3 (DKK3) negatively regulates aerobic glycolysis [HK2, HIF-1, GLUT-1, LDHA and 3-phosphoinositide-dependent protein kinase-1 (PDK-1)] in BxPC-3 cells