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Melatonin has been reported to bind KEAP1, thereby disrupting this interaction and permitting NRF2 to translocate to the nucleus where it can activate antioxidant response element (ARE)-driven gene expression (62, 63)

Previous studies on curcumin have largely focused on its anti-inflammatory or antioxidant activities 12

Other studies showed that Pleurotus ostreatus has the highest concentration of vitamin B1 and B3, and ergosterol (100500 mg/100 g dry weight) present in Agaricus bisporus and Pleurotus ostreatus

I like to spray it onto my face in the morning and use a sponge to dab it out for a more even finish and to prime my skin