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Another critical enzyme of PPP, 6-phosphogluconate dehydrogenase (6PGD), is upregulated in ATC and inhibition of 6PGD is proven to disrupt the doxorubicin-resistant situations in ATC cells [95]

Lee J, Kim H, Lee JE, Shin SJ, Oh S, Kwon G, et al

Common diagnostic methods: Physical Examination & History The vet listens to the heart with a stethoscope to check for murmurs, irregular rhythms, or abnormal sounds

Additionally, baseline alcohol consumption was not available for review in any of the cases, although alcoholic liver disease was an excluded etiology for liver dysfunction at the time of proposed DILI