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Originally, the concept holds the epithelium/endothelium protection achieved against direct injury made by noxious agents by contact in the stomach, as direct cell protection, to be translated unlimitedly to the entire body [35,36,37,38,39,40,41,42]

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Since these two pathways were previously identified as crucial in the AD-related pathway-gene network, we performed cluster analysis on the union of DEGs from all four groups involved in either Neuroactive ligand-receptor interaction or Calcium signaling pathway