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Proposed mechanisms include regulation of endothelial function, influence on blood vessel formation, modulation of inflammatory signaling, and effects on connective tissue-associated processes such as collagen organization

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These effects may be helpful for muscles, tendons, ligaments, joints, and digestive tissue, especially for individuals working toward an active lifestyle, weight loss goals, or improved recovery after physical stress

We designed a FOXO4 peptide which perturbs the FOXO4 interaction with p53